The equilibrium between antagonistic signaling pathways determines the number of synapses in Drosophila.
The number of synapses is a major determinant of behavior and many neural diseases exhibit deviations in that number.However, how signaling pathways control this number DME COCONUT OIL PEPPERMINT FLAVOUR is still poorly understood.Using the Drosophila larval neuromuscular junction, we show here a PI3K-dependent pathway for synaptogenesis which is f